Age 68 years, of Guelph, Ontario passed away at Guelph General Hospital on Tuesday, February 21, 2023. Leaving behind so many lives that she touched including devoted husband, Ron Patterson; predeceased by her husbands Dino Brazolot (1997) and Tim Pagnan (2002). Born to parents Larry (deceased 2019) and Florida Gauvreau. Loving sister to Craig (Sheila, deceased 2023), Art, Randy (deceased 2013), Wendy, Alex (Michelle), and Leslie. Mother to Erin Southwell (Adam), Shauna O’Donnell (Brian), Joseph Pagnan (Jeff), Lee Brazolot (deceased, 2017), Tracy Brazolot (Greg), Christine Thompson (Jeremy), Dina Trussler (Jim), Michael Patterson (Melissa) and Mikaela Patterson. Grandmother to Braedyn, Jordyn, James, Nicholas, Grace, Amberly, Zach, Jesse, James, Trenton (deceased, 2000), Josh, Katie, Rory, Emmett and Giorgia. Karen was also blessed to be great-grandmother to River, Dustin, Chayce, Ayden, Caleb, Landyn, Easton, Peyton, Emma, Kerryn, Daxson, Niamh, Harmony and Novah. Karen will also be missed and remembered by her work family at Remax Real Estate where she cherished so many friendships and many other extended friends and family members. Cremation has taken place. Visitation took place at Gilbert MacIntyre and Son Funeral Home, Hart Chapel, 1099 Gordon St., Guelph, ON, on Monday, February 27th, 2023 from 2-4pm and 6-8pm. A funeral service for Karen then took place at the funeral home on Tuesday, February 28th, 2023, at 11am. In lieu of flowers, donations to the Canadian Cancer Society or Hospice Wellington would be appreciated by the family. Cards are available at the funeral home (519-821-5077) or online at www.gilbertmacintyreandson.com